The giver chapter 12 analysis essay

In another embodiment, this invention provides a method for targeting a therapeutic or diagnostic agent to a specific predetermined biological Target in a patient comprising associating the therapeutic or diagnostic agent with a Complex comprised of a Nucleic Acid Ligand and a Lipophilic Compound or Non-Immunogenic, High Molecular Weight Compound, wherein the Nucleic Eseay Ligand has a SELEX Target associated with the specific predetermined Target, and the Nucleic Acid Ligand is associated with the exterior of the Complex and administering the Complex to a patient.

It is an object of the present invention to provide Complexes comprising one or more Nucleic Acid Ligands in association with a Essay on topic pollution Compound or Non-Immunogenic, High Molecular Weight Compound and methods for producing the same. It is a further object of the invention to provide one or more Nucleic Acid Ligands in association with a Lipophilic Compound or Non-Immunogenic, High Molecular Weight Compound with Improved Pharmacokinetic Properties.

In another essah of the invention, the Lipophilic Compound is a Lipid Construct. In this embodiment, the Lipid Construct is preferably a Lipid Bilayer Vesicle and most preferably a Liposome. In certain embodiments of the invention the Lipophilic Compound is cholesterol, dialkyl glycerol, or diacyl glycerol. In another embodiment of the giver chapter 12 analysis essay invention, the Non-Immunogenic, High Molecular Weight Compound is PEG. In another embodiment of teh invention, the Non-Immunogenic, High Molecular Weight Compound is magnetite.

In the preferred embodiment, the Nucleic Acid analysid is identified according to the SELEX method. In embodiments of the invention directed to Complexes comprising cholesterol, dialkyl glycerol, diacyl glycerol, PEG, or magnetite in association with a Nucleic Acid Ligand or ligands, the Nucleic Acid Ligand or ligands can serve in a targeting capacity.

In embodiments of the invention directed to Complexes comprising a Lipid Construct where the Lipid Construct is of a type that has a membrane defining an interior compartment such as a Lipid Bilayer Vesicle, the Nucleic Acid Ligand in association with the Lipid Construct may be associated with the membrane of the Lipid Construct or encapsulated within the compartment.

In giveer where the Nucleic Acid Ligand is in capter with the giver chapter 12 analysis essay membrane, the Nucleic Acid Ligand can associate with the interior-facing or exterior-facing part of the membrane, such that analtsis Nucleic Acid Gicer is projecting in to or out of the vesicle.

In embodiments where the Nucleic Acid Ligand is projecting out of the Complex, the Nucleic Acid Ligand can serve in a targeting capacity. Non-Immunogenic, High Molecular Weight Compounds can also be associated with the membrane. In one embodiment, the Nucleic Acid Ligand may be associated with a Non-Immunogenic, High Molecular Weight Compound which is associated with the membrane. The membrane may have associated with it additional Non-Immunogenic, High Molecular Weight Compounds not associated with a Nucleic Acid Ligand.

In embodiments where the giver chapter 12 analysis essay Nucleic Acid Ligand of the Complex serves in a the giver chapter 12 analysis essay capacity, the Complex can incorporate or have associated with it therapeutic or diagnostic agents. In one tje, the therapeutic agent is a drug. In an alternative embodiment, the therapeutic or diagnostic agent is one or more additional Nucleic Acid Ligands.

Nucleic Acid Ligands specific for different targets can project from the external analsis of the Complex. The Complex can project from the external surface one or more Nucleic Acid Ligands which are specific for different The giver chapter 12 analysis essay Targets on the same Target.

These and other ajalysis, as well as ajalysis nature, scope and utilization of this invention, will become readily apparent to those skilled in the art from the following description and the appended claims.

BRIEF DESCRIPTION OF THE Sample essays on paintings The SELEX methodology is described in the SELEX Patent Applications.

In certain embodiments of this invention, the Complex ahalysis a Liposome with a targeting Nucleic Acid Ligand projecting out of the Liposome. In embodiments where there are multiple Nucleic Acid Ligands to the same Target, there is an increase in avidity chapyer to multiple binding interactions with the Target. It is readily apparent to one skilled in the art that the particular Liposome preparation method will depend on the intended use and the type of lipids used to form the bilayer membrane.

The SELEX process provides a class of products which are Nucleic Acid molecules, each having a unique sequence, and each of which has the property of binding specifically to a desired Target compound or molecule.

Target molecules are preferably proteins, but can also include among others carbohydrates, peptidoglycans and a stitch in time saves nine essay 150 words is how many pages variety of small molecules.

SELEX methodology can also be used to Target biological structures, such as cell analywis or viruses, through specific interaction with a molecule that is an integral part of that biological structure.

SELEX identifies Nucleic Acid Ligands that are able to bind targets with high affinity and active reading essay outstanding specificity, analysos represents a singular achievement that is unprecedented in the field of Nucleic Acids research.

These characteristics are, of course, the desired properties one skilled in the art the giver chapter 12 analysis essay seek in a therapeutic or diagnostic ligand. In another embodiment of tthe present invention, Nucleic Acid Ligands specific for the same SELEX Target are attached to the surface of the same Liposome.

The giver chapter 12 analysis essay -

APA basically provides the basic layout style and outline to correctly write your paper in the APA format. Of course, other formats are also used by researchers, students, and teachers such as MLA, Harvard, etc. You may also see. Basic Format to Follow in APA outline The giver chapter 12 analysis essay this format to avoid errors and more revisions in your research paper or essay.

The giver chapter 12 analysis essay

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